Gutfeeling labs
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Summary in English

Gutfeeling Labs offers a public service aimed at individuals in the General Public that provides individual information on both bacterial composition and gut flora functions which have potential to promote well-being. 

For example, our analysis of the intestinal flora can identify the proportion of the intestinal flora with potential to produce short fatty acids, which may have the ability to strengthen the gut barrier function and have anti-inflammatory effects. Furthermore, our method can measure the proportion of the intestinal flora with potential to digest lactose and fibers.

Along with the analysis results you will receive information about dietary supplements and food that may influence the intestinal flora positively.

Research studies have shown links between the intestinal flora and health and the knowledge of the importance of intestinal flora for our well-being increases daily. Our analysis can give you a starting point.

Gutfeeling Labs is a company at the SmiLe Incubator, Medicon Village in Lund and was founded by Walter Fischer and Hans Fischer, associate professors in Neuroscience and Immunology at Lund University. 

“We want to offer an economically reasonable intestinal flora analysis and provide useful information on diet and dietary supplements which may influence the gut flora. Each person has his or her own gut flora and knowledge of this, combined with information on relevant food and diet supplements can give a starting point for a possible change – an individual balancing of the intestinal flora,” says Hans Fischer.

Hans Fischer has been studying the intestinal flora for a decade and has shown that a special type of colon inflammation is linked to low levels of Akkermansia, a bacterium that lives in the intestinal mucous layer. “These results kindled my interest in the possibility to promote the growth of bacteria such as Akkermansia” by a change of diet, says Hans Fischer.

Walter Fischer, neurosurgeon, became interested in the intestinal flora in connection with a research study on the effect of immunotherapy in patients with glioblastoma (primary brain cancer) which was published in the prestigious journal Nature communications 2018. In his study, he saw that brain tumors shrank in some patients but not others. 

"There are different theories about why the immune system does not attack cancer cells, but when another research group showed that the presence of the bacterium Akkermansia in the gut was linked to an increased treatment effect of immunotherapy in cancer, I became involved in my brother's work”, says Walter Fischer.

“By knowing about the bacterial diversity of the gut flora, the presence of beneficial bacteria and some relevant gut flora functions, one can have a starting position to relate to when it comes to food and food supplements. By this, one has a better chance to try to increase the proportion of bacteria that produce health-promoting substances,” says Hans Fischer. 

This concept is being tested in a Swedish research study where a dietary fiber is administered to people at risk for developing type 2-diabetes.

By giving the people participating in the study dietary fiber the researchers are trying to stimulate the growth of bacteria which in turn can produce butyric acid. The hypothesis is that Butyric acid will strengthen the intestinal barrier and have anti-inflammatory effects that can counteract the inflammation known to be linked to type 2-diabetes.